With the increase of the number of children with autism, it is necessary to know what is happening on a daily basis. UCF researchers are now more closely considering the link between pregnant women and the development of the fetus.
D. Salah Naser, Latifa Abdelli and UCF Bachelor's Research Assistant Aseela Samsam revealed molecular changes that occur when nerve stem cells are subjected to high levels of acid are often found in processed foods. The study was published on June 19 Scientific reportsIn the journal Nature, UCF scientists have discovered how high the proportional acid (PPA) is, which increases the packaging of food and suppresses the commercially processed grapes and bread, preventing the development of neurons in the brain development of the fetus.
Dr. Naser, who specialized in the Gastroenterology Research Medicine of Burnett School of Biomedical Sciences has started studying the following reports showed that autistic children often suffer from stomach issues such as irritable bowel syndrome. He was surprised by the possible connection between Gutas and the brain and began to study how it was influenced by microorganisms or intestinal bacteria – between autism and those who do not have a condition.
"Studies have shown that high levels of PPA in children with autism infections and outsiders are smoother of microbialism," says Dr. Nasser. "I wanted to know what was the basis."
In the lab scientists have discovered nerve stem cells that exaggerate the PPA to damage the brain cells in several ways. First, acid helps prevent brain cells from reducing the number of neurons and cell cells. Although smooth cells promote the development and protection of neuron function, many heart cells are associated with neurons. They also cause inflammation, which was noted in the brain's brain.
Excessive amount of acid also reduces and damaged roads that use neurons from the rest of the body. Combination of reduced neurons and damaged pathways prevents the brain's ability to communicate, resulting in behavior that are often found in autism children, including repeated behavior, mobility issues and inability to interact with others.
Previous studies between proposed communications between autism and environmental and genetic factors, but Drs. Naser and Abdelli say that their research is the first discovery of molecular communication with elevated levels of PPA, proliferation of glial cells, disturbed with nervous schemes and autism. 18-month training was carried out by self-financing.
PPA is naturally in the intestine and mother's microbiome changes during pregnancy and can lead to increased acid. But d. Naser and Abdelli said eating to eat packed foods containing acid could further increase PPA women's gut, which then crosses the fetus.
More research should be done before clinical conclusion. Next, the research team will examine its conclusions in mice models if you see whether the high PPA maternal diet causes autism to be genetically modified. There is no cure for 59 children, but scientists hope that their conclusions will help prevent unrest.
"This study is the first step to better understanding the autism spectrum disorder," – said UCF scientists. "But we have confidence in the right path to finally learn the autism of autism."
Materials are provided Central Florida University. Originally written by Sutling Wong-Vienneau. Note: The content can be edited by style and length.